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Ivermectin buy online dispersible tablets, such as Iverheal 12 mg, have gained significant attention in recent years due to their potential uses in various medical treatments. Ivermectin itself is a well-established antiparasitic medication that has been in use for decades. Originally developed in the 1970s, ivermectin was initially employed to treat parasitic infections in livestock. Its efficacy and safety profile eventually led to its adaptation for human use, particularly in combating a range of parasitic diseases. 

Mechanism of Action

Ivermectin works by binding to specific chloride channels in the nerve and muscle cells of parasites. This binding causes an increase in the permeability of the cell membrane to chloride ions, leading to paralysis and death of the parasite. This mechanism is particularly effective against a variety of parasitic worms and insects, making ivermectin a versatile antiparasitic agent.

Uses of Iverheal 12 mg

The Iverheal 12 mg tablet is primarily used to treat various parasitic infections. One of the most notable uses of ivermectin is in the treatment of onchocerciasis, also known as river blindness, which is caused by the parasite Onchocerca volvulus. Ivermectin is also effective against other parasitic diseases such as strongyloidiasis and scabies.

In the context of scabies, which is caused by the Sarcoptes scabiei mite, ivermectin has proven to be an effective alternative to topical treatments. It is particularly useful in cases where topical treatments have failed or in institutional outbreaks where topical treatment compliance might be challenging.

Dosage and Administration

The standard dosage of Iverheal 12 mg for treating parasitic infections typically depends on the patient's weight and the specific condition being treated. For example, in the treatment of strongyloidiasis, a single dose of 200 micrograms per kilogram of body weight is usually recommended. However, the dosage can vary, and it is crucial for patients to follow the prescribing healthcare provider’s instructions closely.

The dispersible nature of the tablet makes it convenient for administration, especially in settings where access to clean water is limited. Patients can disperse the tablet in a small amount of liquid, making it easier to swallow, which is particularly beneficial for young children or individuals who have difficulty swallowing pills.

Safety and Side Effects

Ivermectin is generally well-tolerated when used at recommended dosages. Common side effects may include dizziness, nausea, diarrhea, and fatigue. In the treatment of onchocerciasis, a unique set of side effects known as the Mazzotti reaction can occur. This reaction is due to the rapid killing of the microfilariae and includes symptoms such as fever, skin rash, and muscle pain.

It is important for patients to inform their healthcare provider of any other medications they are taking, as well as any pre-existing health conditions, to avoid potential drug interactions and complications.

Controversies and Current Research

In recent years, ivermectin has been the subject of controversy due to its purported use in treating COVID-19. While some early studies and anecdotal reports suggested potential benefits, larger, more rigorous studies have not confirmed its efficacy for this purpose. Leading health organizations, including the World Health Organization (WHO) and the U.S. Food and Drug Administration (FDA), have advised against using ivermectin for COVID-19 outside of clinical trials.

Despite the controversies, ongoing research continues to explore the potential repurposing of ivermectin for various viral infections. Its broad-spectrum antiparasitic activity and established safety profile make it an interesting candidate for further investigation.